Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone
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منابع مشابه
Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone.
Calcium homeostasis is a tightly regulated process involving the co-ordinated efforts of the skeleton, kidney, parathyroid glands and intestine. Neoplasms can alter this homeostasis indirectly through the production of endocrine factors resulting in humoral hypercalcaemia of malignancy. Relatively common with breast and lung cancer, this paraneoplastic condition is most often due to tumour prod...
متن کاملBasic mechanisms responsible for osteolytic and osteoblastic bone metastases.
Certain solid tumors metastasize to bone and cause osteolysis and abnormal new bone formation. The respective phenotypes of dysregulated bone destruction and bone formation represent two ends of a spectrum, and most patients will have evidence of both. The mechanisms responsible for tumor growth in bone are complex and involve tumor stimulation of the osteoclast and the osteoblast as well as th...
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آب حاصل از بارش منبع تأمین نیازهای بی شمار جانداران به ویژه انسان است و هرگونه کاهش در کم و کیف آن مستقیماً حیات موجودات زنده را تحت تأثیر منفی قرار می دهد. نوسان سال به سال بارش از ویژگی های اساسی و بسیار مهم بارش های سالانه ایران محسوب می شود که آثار زیان بار آن در تمام عرصه های اقتصادی، اجتماعی و حتی سیاسی- امنیتی به نحوی منعکس می شود. چون میزان آب ناشی از بارش یکی از مولفه های اصلی برنامه ...
15 صفحه اولHypercalcaemia and osteolytic bone lesions in chronic lymphocytic leukaemia.
Prescott LF, King IS, Brown L, Balali M, Adriaenssens PI. HPLC in clinical pharmacological studies of analgesic drugs. Proceedings of the Analytical Division of the Chemical Society 1979;16:300-2. 2 Aarbakke J. Clinical pharmacokinetics of phenylbutazone. Clin Pharmacokinet 1978;3 :369-80. 3 Wramner T. A case of poisoning with 10 grams of Butazolidin. Acta Rheum Scand 1957;3:82-91. 4 Juul J. Ac...
متن کاملProstate cancer bone metastases promote both osteolytic and osteoblastic activity.
Advanced prostate cancer is frequently accompanied by the development of metastasis to bone. In the past, prostate cancer bone metastases were characterized as being osteoblastic (i.e., increasing bone density) based on radiographs. However, emerging evidence suggests that development of prostate cancer bone metastases requires osteoclastic activity in addition to osteoblastic activity. The com...
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ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2005
ISSN: 1351-0088,1479-6821
DOI: 10.1677/erc.1.00543